Publications

Clinical Neurophysiology Journal - Editor's Choice

Professor Robert Chen
Editor-in-Chief, Clinical Neurophysiology

The Editor’s Choice—

Neurorehabilitation in spinal cord injury: Increased cortical activity through tDCS and robotic gait training

Clinical Neurophysiology Volume 173 (May 2025)

Daniel Boari Coelho, Artur Cesar Aquino dos Santos, João Ricardo Sato, Marcel Simis, Felipe Fregni, Linamara Rizzo Battistella

There is increasing interest in using non-invasive neuromodulation to improve the outcome of neurorehabilitation. In this volume of Clinical Neurophysiology, Coelho et al. reported a randomized, controlled trial of anodal vs. sham transcranial direct current stimulation (tDCS) of the leg representation of the motor cortex (M1) followed by robot assisted gait training in 26 individuals with incomplete spinal cord injury. The active tDCS group showed higher oxyhemoglobin concentration in the supplementary motor area and the M1, which correlated with improvement measured with the Walking Index Spinal Cord Injury II scale. These results support the potential of using neuromodulation to promote brain plasticity and increase cortical activities, which may improve rehabilitation outcome

Editor Choice- Highlights (May 2025)

Read editor’s choice collection of articles:

Machine learning-driven Heckmatt grading in facioscapulohumeral muscular dystrophy: A novel pathway for musculoskeletal ultrasound analysis
2025 April Vol. 172
Trigeminal reflex testing abnormalities as a predictive model for distinguishing classical and idiopathic trigeminal neuralgia
2025 March Vol. 171
High-density theta oscillatory-modulated tDCS over the parietal cortex for targeted memory enhancement
2025 February Vol. 170
Association of abnormal cortical inhibition and clinical outcomes in patients at clinical high risk for psychosis
2025 January Vol. 169

EEG aperiodic dynamics from early through late childhood: Associations with ADHD, cognition, and development
2024 December Vol. 168
Breakdown of TMS evoked EEG signal propagation within the default mode network in Alzheimer’s disease
2024 November Vol. 167
Cortical activation in REM behavior disorder mimics voluntary movement. An electroencephalography study
2024 October Vol. 166
Role of Intraoperative Electroencephalography in Predicting Postoperative Delirium in Patients Undergoing Cardiovascular Surgeries
2024 August Vol. 164
Emotional facial expression and perioral motor functions of the human auditory cortex
2024 July Vol. 163
Trait-dependent effects of theta burst stimulation after psychosocial stress: a sham-controlled study in healthy individuals
2024 June Vol. 162
Whole-body fasciculation detection in amyotrophic lateral sclerosis using motor unit MRI.
2024 May Vol. 161
Distinct MRI-based functional and structural connectivity for antidepressant response prediction in major depressive disorder.
2024 April Vol. 160
Axonal excitability as an early biomarker of nerve involvement in hereditary transthyretin amyloidosis.
2024 March Vol. 159
Abnormal motor cortical plasticity as a useful neurophysiological biomarker for Alzheimer’s disease pathology
2024 February Vol. 158
Parkinsonian rest tremor can be distinguished from voluntary hand movements based on subthalamic and cortical activity
2024 January Vol. 157

Artificial intelligence-based classification of motor unit action potentials in real-world needle EMG recordings
2023 December Vol. 156
DICOM® integrated EEG data: A first clinical implementation of the new DICOM standard for neurophysiology data
2023 November Vol. 155
Ultrafast review of ambulatory EEGs with deep learning
2023 October Vol. 154
Frequency-dependent tuning of the human vestibular "sixth sense" by transcranial oscillatory currents
2023 September Vol. 153
Clinical neurophysiological interrogation of motor slowing: A critical step towards tuning adaptive deep brain stimulation.
2023 August Vol. 152
Deficient GABABergic and glutamatergic excitability in the motor cortex of patients with long-COVID and cognitive impairment.
2023 July Vol. 151
Clinical diagnostic utility of transcranial magnetic stimulation in neurological disorders. Updated report of an IFCN committee
2023 June Vol. 150
Image analysis can reliably quantify median nerve echogenicity and texture changes in patients with carpal tunnel syndrome
2023 May Vol. 149
Cortical reactivity to transcranial magnetic stimulation predicts risk of post-stroke delirium
2023 April Vol. 148
Passive functional mapping of receptive language cortex during general anesthesia using electrocorticography
2023 March Vol. 147
Quantitative EEG signatures of delirium and coma in mechanically ventilated ICU patients
2023 February Vol. 146
Detailed magnetoelectric analysis of a nerve impulse propagation along the brachial plexus
2023 January Vol. 145

MRI-guided focused-ultrasound thalamotomy in essential tremor: Immediate and delayed changes in cortico-muscular coherence and cortico-cortical out-strength
2022 December Vol. 144
Automated EEG-based prediction of delayed cerebral ischemia after subarachnoid hemorrhage
2022 November Vol. 143
Vagal nerve stimulation cycles alter EEG connectivity in drug-resistant epileptic patients: A study with graph theory metrics
2022 October Vol. 142
Sub-scalp electroencephalography: A next-generation technique to study human neurophysiology
2022 September Vol. 141
Transcranial magnetic stimulation of the brain: What is stimulated?—A consensus and critical position paper
2022 August Vol. 140
Virtual implantation using conventional scalp EEG delineates seizure onset and predicts surgical outcome in children with epilepsy
2022 July Vol. 139
Transcranial electrical stimulation elicits short and long latency responses in the tongue muscles
2022 June Vol. 138
EEG spectral exponent as a synthetic index for the longitudinal assessment of stroke recovery
2022 May Vol. 137
Review of techniques useful for the assessment of sensory small fiber neuropathies: Report from an IFCN expert group
2022 April Vol. 136
Non-invasive transcranial ultrasound stimulation for neuromodulation
2022 March Vol. 135
Minimum standards for inpatient long-term video-EEG monitoring: A clinical practice guideline of the international league against epilepsy and international federation of clinical neurophysiology
2022 February Vol. 134
TMS-induced brain connectivity modulation in Genetic Generalized Epilepsy
2022 January Vol. 133

Machine learning for predicting levetiracetam treatment response in temporal lobe epilepsy
2021 December Vol. 132, Issue 12
Early nociceptive evoked potentials (NEPs) recorded from the scalp
2021 November Vol. 132, Issue 11
The reliability of cerebellar brain inhibition
2021 October Vol. 132, Issue 10
Highly consistent temporal lobe interictal spike networks revealed from foramen ovale electrodes
2021 September Vol. 132, Issue 9
Subclinical epileptiform activity accelerates the progression of Alzheimer’s disease: A long-term EEG study
2021 August Vol. 132, Issue 8
Altered interhemispheric signal propagation in schizophrenia and depression
2021 July Vol. 132, Issue 7
Alpha power decrease in quantitative EEG detects development of cerebral infarction after subarachnoid hemorrhage early
2021 June Vol. 132, Issue 6
Automated seizure detection using wearable devices: A clinical practice guideline of the International League Against Epilepsy and the International Federation of Clinical Neurophysiology
2021 May Vol. 132, Issue 5
Chronic fatigue syndrome: Abnormally fast muscle fiber conduction in the membranes of motor units at low static force load
2021 April Vol. 132, Issue 4
Training in the practice of noninvasive brain stimulation: Recommendations from an IFCN committee
2021 March Vol. 132, Issue 3
Electrodiagnostic assessment of the autonomic nervous system: A consensus statement endorsed by the American Autonomic Society, American Academy of Neurology, and the International Federation of Clinical Neurophysiology
2021 February Vol. 132, Issue 2
Safety and recommendations for TMS use in healthy subjects and patient populations, with updates on training, ethical and regulatory issues: Expert Guideline
2021 January Vol. 132, Issue 1

Association of cortical spreading depression and seizures in patients with medically intractable epilepsy
2020 December Vol. 131, Issue 12
Clinical and advanced neurophysiology in the prognostic and diagnostic evaluation of disorders of consciousness: review of an IFCN-endorsed expert group
2020 November Vol. 131, Issue 11
Stratifying chronic stroke patients based on the influence of contralesional motor cortices: An inter-hemispheric inhibition study
2020 October Vol. 131, Issue 10
Age-related decline of neuroplasticity to intermittent theta burst stimulation of the lateral prefrontal cortex and its relationship with late-life memory performance
2020 September Vol. 131, Issue 9
Separating posterior-circulation stroke from vestibular neuritis with quantitative vestibular testing
2020 August Vol. 131, Issue 8
Cortical network dysfunction revealed by magnetoencephalography in carriers of spinocerebellar ataxia 1 or 2 mutation
2020 July Vol. 131, Issue 7
Latency of subthalamic nucleus deep brain stimulation-evoked cortical activity as a potential biomarker for postoperative motor side effects
2020 June Vol. 131, Issue 6
Characterizing vocal tremor in progressive neurological diseases via automated acoustic analyses
2020 May Vol. 131, Issue 5
Visualization of electrophysiological activity at the carpal tunnel area using magnetoneurography
2020 April Vol. 131, Issue 4
An Automatic Detection Method for 40-Hz Auditory Steady State Response and its Application in Prognosis of Comatose Patients
2020 March Vol. 131, Issue 3
Evidence-based guidelines on the therapeutic use of repetitive transcranial magnetic stimulation (rTMS): An update (2014–2018)
2020 February Vol. 131, Issue 2
Measurement of axonal excitability: Consensus guidelines
2020 January Vol. 131, Issue 1

Seventy years of our journal,
An electroencephalographer recalls the history of the Federation on the 70th anniversary of its journal, Clinical Neurophysiology,
An electromyographer recalls the history of the Federation on the 70th anniversary of its journal, Clinical Neurophysiology,
2019 December Vol. 130, Issue 12
Analysis of electrooculography signals for the detection of Myasthenia Gravis
2019 November Vol. 130, Issue 11
Stability of a chronic implanted brain-computer interface in late-stage amyotrophic lateral sclerosis
2019 October Vol. 130, Issue 10
Standards for quantification of EMG and neurography
2019 September Vol. 130, Issue 9
Seizures from transcranial magnetic stimulation 2012–2016: Results of a survey of active laboratories and clinics
2019 August Vol. 130, Issue 8
Brain networks and their relevance for stroke rehabilitation
2019 July Vol. 130, Issue 7
Botulinum neurotoxin serotype D – A potential treatment alternative for BoNT/A and B non-responding patients
2019 June Vol. 130, Issue 6
Clinical utility and prospective of TMS-EEG
2019 May Vol. 130, Issue 5
Assessing blink reflex circuits by three different afferent routes in Parkinson’s disease
2019 April Vol. 130, Issue 4
Cortical networks are disturbed in people with cirrhosis even in the absence of neuropsychometric impairment
2019 March Vol. 130, Issue 3
Interictal spike connectivity in human epileptic neocortex
2019 February Vol. 130, Issue 2
Recommendations of the International Society of Intraoperative Neurophysiology for intraoperative somatosensory evoked potentials
2019 January Vol. 130, Issue 1

Indications for neuromuscular ultrasound: Expert opinion and review of the literature
2018 December Vol. 129, Issue 12
Decreasing subthalamic deep brain stimulation frequency reverses cognitive interference during gait initiation in Parkinson’s disease
2018 November Vol. 129, Issue 11
Fasciculation intensity and disease progression in amyotrophic lateral sclerosis
2018 October Vol. 129, Issue 10
Multi-component intrinsic brain activities as a safe alternative to cortical stimulation for sensori-motor mapping in neurosurgery
2018 September Vol. 129, Issue 9
Implementing Motor Unit Number Index (MUNIX) in a large clinical trial: Real world experience from 27 centres
2018 August Vol. 129, Issue 8
Decrease of motor cortex excitability following exposure to a 20 Hz magnetic field as generated by a rotating permanent magnet
2018 July Vol. 129, Issue 7
Phantom somatosensory evoked potentials following selective intraneural electrical stimulation in two amputees
2018 June Vol. 129, Issue 6
Clinical utility of EEG in diagnosing and monitoring epilepsy in adults
2018 May Vol. 129, Issue 5
Vestibulo-cochlear function in inflammatory neuropathies
2018 April Vol. 129, Issue 4
Sleep patterns associated with the severity of impairment in a large cohort of patients with chronic disorders of consciousness
2018 March Vol. 129, Issue 3
Somatosensory Evoked Potentials and Central Motor Conduction Times in children with dystonia and their correlation with outcomes from Deep Brain Stimulation of the Globus pallidus internus
2018 February Vol. 129, Issue 2
Abnormal functional connectivity of high-frequency rhythms in drug-naïve schizophrenia
2018 January Vol. 129, Issue 1

Ear-EEG detects ictal and interictal abnormalities in focal and generalized epilepsy – A comparison with scalp EEG monitoring
2017 December Vol. 128 Issue 12
Long term correlation of subthalamic beta band activity with motor impairment in patients with Parkinson’s disease
2017 November Vol. 128 Issue 11
The standardized EEG electrode array of the IFCN
2017 October Vol. 128 Issue 10
Low intensity transcranial electric stimulation: Safety, ethical, legal regulatory and application guidelines
2017 September Vol. 128 Issue 9
Reduced electrode arrays for the automated detection of rhythmic and periodic patterns in the intensive care unit: Frequently tried, frequently failed?
2017 August Vol. 128 Issue 8
A novel methodology for assessing laryngeal and vagus nerve integrity in patients under general anesthesia
2017 July Vol. 128 Issue 7
The evolution of motor cortical dysfunction in amyotrophic lateral sclerosis
2017 June Vol. 128 Issue 6
Parietomotor connectivity in the contralesional hemisphere after stroke: A paired-pulse TMS study
2017 May Vol. 128 Issue 5
Early disturbances in multimodal evoked potentials as a prognostic factor for long-term disability in relapsing-remitting multiple sclerosis patients
2017 April Vol. 128 Issue 4
Pain perception in patients with chronic disorders of consciousness: What can limbic system tell us?
2017 March Vol. 128 Issue 3
TMS combined with EEG in genetic generalized epilepsy: A phase II diagnostic accuracy study
2017 February Vol. 128 Issue 2
Haemodialysis alters peripheral nerve morphology in end-stage kidney disease
2017 January Vol. 128 Issue 1

The significance of ultrasonographic carpal tunnel outlet measurements in the diagnosis of carpal tunnel syndrome
2016 December Vol. 127 Issue 12
Motor cortical dysfunction develops in spinocerebellar ataxia type 3
2016 November Vol. 127 Issue 11
Intraoperative spinal cord monitoring using low intensity transcranial stimulation to remove post-activation depression of the H-reflex
2016 October Vol. 127 Issue 10
The relationship between seizures, interictal spikes and antiepileptic drugs
2016 September Vol. 127 Issue 9
Disease-specific sparing of the anterior semicircular canals in bilateral vestibulopathy
2016 August Vol. 127 Issue 8
Brain areas with epileptic high frequency oscillations are functionally isolated in MEG virtual electrode networks
2016 July Vol. 127 Issue 7
Cortical correlates of susceptibility to upper limb freezing in Parkinson’s disease
2016 June Vol. 127 Issue 6
Normal pressure hydrocephalus: Increase of utricular input in responders to spinal tap test
2016 May Vol. 127 Issue 5
Ascending vestibular drive is asymmetrically distributed to the inferior oblique motoneuron pools in a subset of hemispheric stroke survivors
2016 April Vol. 127 Issue 4
Language mapping using high gamma electrocorticography, fMRI, and TMS versus electrocortical stimulation
2016 March Vol. 127 Issue 3
Short pauses in thalamic deep brain stimulation promote tremor and neuronal bursting
2016 February Vol. 127 Issue 2
Yield of MRI, high-density electric source imaging (HD-ESI), SPECT and PET in epilepsy surgery candidates
2016 January Vol. 127 Issue 1