The Masterclass by IFCN was created in response to a call from IFCN member societies for more high quality, complimentary, online educational content. The series will provide a new presentation several times throughout the year from top clinical neurophysiologists around the world, and each will include time for discussion with the lecturer following the presentation.
Providing the best in contemporary clinical neurophysiology education delivered in the most optimal format is the primary educational goal of the IFCN. As such, Masterclass by IFCN will be available complimentary to all registrants.
Threshold tracking transcranial magnetic stimulation (TMS) is an advanced technique for assessing cortical excitability in the human motor cortex. It has provided key pathophysiological insights in motor neuron disease (MND)/amyotrophic lateral sclerosis (ALS), particularly by confirming cortical hyperexcitability as a central mechanism linked to motor neuron degeneration, disease progression, and clinical presentation. Beyond its research value, threshold tracking TMS has become an important diagnostic tool, allowing for earlier and more accurate diagnosis of ALS/MND. The recent commercialisation of the threshold tracking TMS technique (MagXite) has enabled clinical translation. This presentation will explore its pathogenic, prognostic, and diagnostic roles, as well as its growing utility in clinical trials."
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